AML (M0)

Acute Myeloblastic Leukemia with Minimal Differentitaion

• Pancytopenia.
  
  
• MPO, PAS, and NSE negative.
  
  
• No particular chromosomeal abnormalities Negative for lymphoid antigens.
  
  
• Hope for more than 20 % of the blasts to have one or more myeloid antigens (CD 13, CD 33, CD 11b, CD 34, HLA-DR (aids in diagnosis).
  
  
• Constitutes less than 5 % of myeloid leukemias.

PROGNOSIS

Poor due to poor response to chemotherapy