Glossary of Terms
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  Maturation Chart
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Glossary of Terms Study Aid Chart Maturation Chart Resource Links
Cytochemistry Morphology Others
slide Cells Nucleus Nucleoli Cytoplasm
M0
Poorly differentiated blasts Fine lacy chromatin pattern: round Distinct, one or more Moderated, basophilic
M1
Blasts large, regularMinimal differentiation Fine lacy chromatin pattern: round Distinct, one or more No cytoplasmic granulation
M2
Very Large;
granulated blasts predominated		 Fine lacy chromatin pattern: round One or more No cytoplasmic granulation; Occasional auer rods may be present
M3
Very large hypergranuated; Promyelocytes Varies in size and shape: May be reniform or bilobed;Can be hidden by granules One or more Few or many primary granules, Bundles "faggots" of Auer Rod may be present
M4
Both monocytic and myelocytic differentiation Monocytic - folded nuclei May be present Monocytic-abundant cytoplasm; Myelocytic-may have primary & secondary granules
M5
Poorly differentiated
and well differentiated variants of monoblasts
& promyelocytes		 Delicate folding or lobulation May be present Abundant
M6
Myeloblasts and promyelocytes
Dysplastic erythroblasts

May be multinucleated;
Megaloblastoid changes

   Cytoplasmic budding, vacuolization, megaloblastiod changes; Auer rods may be present
M7

Variable morphology-small cells with scant cytoplasm to large with moderate cytoplasm; megakaryoblasts and atypical megakaryocytes
-
   Cytoplasmic projections may be present; Occasionally azurophilic granules are seen

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